Month: September 2020

A global network for network medicine

Bradley A. Maron, Lucia Altucci, Jean-Luc Balligand, Jan Baumbach, Peter Ferdinandy, Sebastiano Filetti, Paolo Parini, Enrico Petrillo, Edwin K. Silverman, Albert-László Barabási, Joseph Loscalzo & International Network Medicine Consortium
npj Systems Biology and Applications volume 6, Article number: 29 (2020)

 

Network Medicine is now an established scientific discipline, having generated key insights on integrated mechanisms underlying complex human diseases. The next discovery phase will emphasize innovating analytics that optimize networks for advancing precision medicine. Accomplishing this goal will require organizing a scientifically diverse team studying big datasets shared globally.

Source: www.nature.com

Complexity science approach to economic crime

János Kertész and Johannes Wachs discuss how complexity science and network science are particularly useful for identifying and describing the hidden traces of economic misbehaviour such as fraud and corruption.

 

Nature Reviews Physics (2020)

Source: www.nature.com

AI and Its New Winter: from Myths to Realities

Luciano Floridi 
Philosophy & Technology volume 33, pages1–3(2020)

 

The trouble with seasonal metaphors is that they are cyclical. If you say that artificial intelligence (AI) got through a bad winter, you must also remember that winter will return, and you better be ready. An AI winter is that stage when technology, business, and the media get out of their warm and comfortable bubble, cool down, temper their sci-fi speculations and unreasonable hypes, and come to terms with what AI can or cannot really do as a technology (Floridi 2019), without exaggeration. Investments become more discerning, and journalists stop writing about AI, to chase some other fashionable topics and fuel the next fad.

Source: link.springer.com

Electronically integrated, mass-manufactured, microscopic robots

Marc Z. Miskin, Alejandro J. Cortese, Kyle Dorsey, Edward P. Esposito, Michael F. Reynolds, Qingkun Liu, Michael Cao, David A. Muller, Paul L. McEuen & Itai Cohen 
Nature volume 584, pages557–561(2020)

 

Fifty years of Moore’s law scaling in microelectronics have brought remarkable opportunities for the rapidly evolving field of microscopic robotics1,2,3,4,5. Electronic, magnetic and optical systems now offer an unprecedented combination of complexity, small size and low cost6,7, and could be readily appropriated for robots that are smaller than the resolution limit of human vision (less than a hundred micrometres)8,9,10,11. However, a major roadblock exists: there is no micrometre-scale actuator system that seamlessly integrates with semiconductor processing and responds to standard electronic control signals. Here we overcome this barrier by developing a new class of voltage-controllable electrochemical actuators that operate at low voltages (200 microvolts), low power (10 nanowatts) and are completely compatible with silicon processing. To demonstrate their potential, we develop lithographic fabrication-and-release protocols to prototype sub-hundred-micrometre walking robots. Every step in this process is performed in parallel, allowing us to produce over one million robots per four-inch wafer. These results are an important advance towards mass-manufactured, silicon-based, functional robots that are too small to be resolved by the naked eye.

Source: www.nature.com

Towards a general theory of the major cooperative evolutionary transitions

Towards a general theory of the major cooperative evolutionary transitions
John E.Stewart

Biosystems
Volume 198, December 2020, 104237

 

Major Cooperative Evolutionary Transitions occur when smaller-scale entities cooperate together to give rise to larger-scale entities that evolve and adapt as coherent wholes. Key examples of cooperative transitions are the emergence of the complex eukaryote cell from communities of simpler cells, the transition from eukaryote cells to multicellular organisms, and the organization of humans into complex, modern societies. A number of attempts have been made to develop a general theory of the major cooperative transitions. This paper begins by critiquing key aspects of these previous attempts. Largely, these attempts comprise poorly-integrated collections of separate models that were each originally developed to explain particular transitions. In contrast, this paper sets out to identify processes that are common to all cooperative transitions. It develops an alternative theoretical framework known as Management Theory. This general framework suggests that all major cooperative transitions are the result of the emergence of powerful, evolvable ‘managers’ that derive benefit from using their power to organize smaller-scale entities into larger-scale cooperatives. Management Theory is a contribution to the development of a general, “all levels” understanding of major cooperative transitions that is capable of identifying those features that are level-specific, those that are common across levels and those that are involved in trends across levels.

Source: www.sciencedirect.com