Fengli Xu, Qi Wang, Esteban Moro, Lin Chen, Arianna Salazar Miranda, Marta C. González, Michele Tizzoni, Chaoming Song, Carlo Ratti, Luis Bettencourt, Yong Li & James Evans
Nature Human Behaviour (2025)

The lived experience of urban life is shaped by personal mobility through dynamic relationships and resources, marked not only by access and opportunity, but also inequality and segregation. The recent availability of fine-grained mobility data and context attributes ranging from venue type to demographic mixture offer researchers a deeper understanding of experienced inequalities at scale, and pose many new questions. Here we review emerging uses of urban mobility behaviour data, and propose an analytic framework to represent mobility patterns as a temporal bipartite network between people and places. As this network reconfigures over time, analysts can track experienced inequality along three critical dimensions: social mixing with others from specific demographic backgrounds, access to different types of facilities, and spontaneous adaptation to unexpected events, such as epidemics, conflicts or disasters. This framework traces the dynamic, lived experiences of urban inequality and complements prior work on static inequalities experience at home and work. Xu et al. review applications of urban mobility behaviour data and propose a temporal bipartite network that reveals mobility patterns between people and places. It helps to track urban inequalities in social mixing, facility access and adaptation.

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Moritz U. G. Kraemer, et al.

Nature volume 638, pages 623–635 (2025)

Infectious disease threats to individual and public health are numerous, varied and frequently unexpected. Artificial intelligence (AI) and related technologies, which are already supporting human decision making in economics, medicine and social science, have the potential to transform the scope and power of infectious disease epidemiology. Here we consider the application to infectious disease modelling of AI systems that combine machine learning, computational statistics, information retrieval and data science. We first outline how recent advances in AI can accelerate breakthroughs in answering key epidemiological questions and we discuss specific AI methods that can be applied to routinely collected infectious disease surveillance data. Second, we elaborate on the social context of AI for infectious disease epidemiology, including issues such as explainability, safety, accountability and ethics. Finally, we summarize some limitations of AI applications in this field and provide recommendations for how infectious disease epidemiology can harness most effectively current and future developments in AI.

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Elma Dervić, Katharina Ledebur, Stefan Thurner & Peter Klimek
Scientific Data volume 12, Article number: 215 (2025)

Comorbidity networks have become a valuable tool to support data-driven biomedical research. Yet, studies often are severely hindered by the availability of the necessary comprehensive data, often due to the sensitivity of health care information. This study presents a population-wide comorbidity network dataset derived from 45 million hospital stays of 8.9 million patients over 17 years in Austria. We present co-occurrence networks of hospital diagnoses, stratified by age, sex, and observation period in a total of 96 different subgroups. For each of these groups we report a range of association measures (e.g., count data, and odds ratios) for all pairs of diagnoses. The dataset provides the possibility to researchers to create their own, tailor-made comorbidity networks from real patient data that can be used as a starting point in quantitative and machine learning methods. This data platform is intended to lead to deeper insights into a wide range of epidemiological, public health, and biomedical research questions.

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Guillaume St-Onge, Jessica T. Davis, Laurent Hébert-Dufresne, Antoine Allard, Alessandra Urbinati, Samuel V. Scarpino, Matteo Chinazzi & Alessandro Vespignani 
Nature Medicine (2025)

Aircraft wastewater surveillance has been proposed as a new approach to monitor the global spread of pathogens. Here we develop a computational framework providing actionable information for the design and estimation of the effectiveness of global aircraft-based wastewater surveillance networks (WWSNs). We study respiratory diseases of varying transmission potential and find that networks of 10–20 strategically placed wastewater sentinel sites can provide timely situational awareness and function effectively as an early warning system. The model identifies potential blind spots and suggests optimization strategies to increase WWSN effectiveness while minimizing resource use. Our findings indicate that increasing the number of sentinel sites beyond a critical threshold does not proportionately improve WWSN capabilities, emphasizing the importance of resource optimization. We show, through retrospective analyses, that WWSNs can notably shorten detection time for emerging pathogens. The approach presented offers a realistic analytic framework for the analysis of WWSNs at airports.

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Waldemar Karwowski, et al.

International Journal of Production Research

Contemporary society faces a growing set of complex issues representing significant socioeconomic, health and well-being, environmental, and sustainability challenges. The discipline of industrial and systems engineering (ISE) can play an important role in addressing these issues. This paper identifies and discusses eight grand challenges for ISE. These grand challenges are (1) Artificial Intelligence (AI) For Business and Personal Use: Decision-Making and System Design and Operations, (2) Cybersecurity and Resilience, (3) Sustainability: Environment, Energy and Infrastructure, (4) Health Issues, (5) Social Issues, (6) Logistics and Supply Chain, (7) System Integration and Operations: Humans, Automation, and AI, and (8) Industrial and Systems Engineering Education. The discussed grand challenges were derived by accomplished ISE professionals who are the authors of this paper. The implications of the ISE grand challenges for education, training, research, and implementation of ISE principles and methodologies for the benefit of global society are discussed.

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