Modeling Autopoiesis and Cognition with Reaction Networks

Francis Heylighen, Evo Busseniers

Maturana and Varela defined an autopoietic system as a self-regenerating network of processes. We reinterpret and elaborate this conception starting from a process ontology and its formalization in terms of reaction networks and chemical organization theory. An autopoietic organization can be modelled as a network of “molecules” (components) undergoing reactions, which is (operationally) closed and self-maintaining. Such organizations, being attractors of a dynamic system, tend to self-organize—thus providing a model for the origin of life. However, in order to survive in a variable environment, they must also be resilient, i.e. able to recover from perturbations. According to the cybernetic law of requisite variety, this requires cognition, i.e. the ability to recognize and compensate perturbations. Such cognition becomes more effective as it learns to accurately anticipate perturbations by discovering invariant patterns in its interactions with the environment. Nevertheless, the resulting predictive model remains a subjective construction. Such implicit model cannot be interpreted as an objective representation of external reality, because the autopoietic system does not have direct access to that reality, and there is in general no isomorphism between internal and external processes.

Read the full article at: researchportal.vub.be

Provenance of life: Chemical autonomous agents surviving through associative learning

Stuart Bartlett and David Louapre
Phys. Rev. E 106, 034401

We present a benchmark study of autonomous, chemical agents exhibiting associative learning of an environmental feature. Associative learning systems have been widely studied in cognitive science and artificial intelligence but are most commonly implemented in highly complex or carefully engineered systems, such as animal brains, artificial neural networks, DNA computing systems, and gene regulatory networks, among others. The ability to encode environmental information and use it to make simple predictions is a benchmark of biological resilience and underpins a plethora of adaptive responses in the living hierarchy, spanning prey animal species anticipating the arrival of predators to epigenetic systems in microorganisms learning environmental correlations. Given the ubiquitous and essential presence of learning behaviors in the biosphere, we aimed to explore whether simple, nonliving dissipative structures could also exhibit associative learning. Inspired by previous modeling of associative learning in chemical networks, we simulated simple systems composed of long- and short-term memory chemical species that could encode the presence or absence of temporal correlations between two external species. The ability to learn this association was implemented in Gray-Scott reaction-diffusion spots, emergent chemical patterns that exhibit self-replication and homeostasis. With the novel ability of associative learning, we demonstrate that simple chemical patterns can exhibit a broad repertoire of lifelike behavior, paving the way for in vitro studies of autonomous chemical learning systems, with potential relevance to artificial life, origins of life, and systems chemistry. The experimental realization of these learning behaviors in protocell or coacervate systems could advance a new research direction in astrobiology, since our system significantly reduces the lower bound on the required complexity for autonomous chemical learning.

Read the full article at: link.aps.org

Assessing the robustness of critical behavior in stochastic cellular automata

Sidney Pontes-Filho, Pedro G.Lind, Stefano Nichele

Physica D: Nonlinear Phenomena, Volume 441, December 2022, 133507

Read the full article at: www.sciencedirect.com

There is evidence that biological systems, such as the brain, work at a critical regime robust to noise, and are therefore able to remain in it under perturbations. In this work, we address the question of robustness of critical systems to noise. In particular, we investigate the robustness of stochastic cellular automata (CAs) at criticality. A stochastic CA is one of the simplest stochastic models showing criticality. The transition state of stochastic CA is defined through a set of probabilities. We systematically perturb the probabilities of an optimal stochastic CA known to produce critical behavior, and we report that such a CA is able to remain in a critical regime up to a certain degree of noise. We present the results using error metrics of the resulting power-law fitting, such as Kolmogorov–Smirnov statistic and Kullback–Leibler divergence. We discuss the implication of our results in regards to future realization of brain-inspired artificial intelligence systems.

A machine learning model to identify corruption in México’s public procurement contracts

Andrés Aldana, Andrea Falcón-Cortés, Hernán Larralde

The costs and impacts of government corruption range from impairing a country’s economic growth to affecting its citizens’ well-being and safety. Public contracting between government dependencies and private sector instances, referred to as public procurement, is a fertile land of opportunity for corrupt practices, generating substantial monetary losses worldwide. Thus, identifying and deterring corrupt activities between the government and the private sector is paramount. However, due to several factors, corruption in public procurement is challenging to identify and track, leading to corrupt practices going unnoticed. This paper proposes a machine learning model based on an ensemble of random forest classifiers, which we call hyper-forest, to identify and predict corrupt contracts in México’s public procurement data. This method’s results correctly detect most of the corrupt and non-corrupt contracts evaluated in the dataset. Furthermore, we found that the most critical predictors considered in the model are those related to the relationship between buyers and suppliers rather than those related to features of individual contracts. Also, the method proposed here is general enough to be trained with data from other countries. Overall, our work presents a tool that can help in the decision-making process to identify, predict and analyze corruption in public procurement contracts.

Read the full article at: arxiv.org

A multinational Delphi consensus to end the COVID-19 public health threat

Jeffrey V. Lazarus, et al.

Nature (2022)

Despite notable scientific and medical advances, broader political, socioeconomic and behavioural factors continue to undercut the response to the COVID-19 pandemic1,2. Here we convened, as part of this Delphi study, a diverse, multidisciplinary panel of 386 academic, health, non-governmental organization, government and other experts in COVID-19 response from 112 countries and territories to recommend specific actions to end this persistent global threat to public health. The panel developed a set of 41 consensus statements and 57 recommendations to governments, health systems, industry and other key stakeholders across six domains: communication; health systems; vaccination; prevention; treatment and care; and inequities. In the wake of nearly three years of fragmented global and national responses, it is instructive to note that three of the highest-ranked recommendations call for the adoption of whole-of-society and whole-of-government approaches1, while maintaining proven prevention measures using a vaccines-plus approach2 that employs a range of public health and financial support measures to complement vaccination. Other recommendations with at least 99% combined agreement advise governments and other stakeholders to improve communication, rebuild public trust and engage communities3 in the management of pandemic responses. The findings of the study, which have been further endorsed by 184 organizations globally, include points of unanimous agreement, as well as six recommendations with >5% disagreement, that provide health and social policy actions to address inadequacies in the pandemic response and help to bring this public health threat to an end.

Read the full article at: www.nature.com